| SUV | Sport Utility Vehicle |
| SOAP | Simple Object Access Protocol |
| SEBI | Securities and Exchange Board of India |
| SIDBI | Small Industries Development Bank of India |
| SLR | Single Lens Reflex |
| SSLC | Secondary School Leaving Certificate |
| SSB | Service Selection Board |
| SAARC | South Asian Association for Regional Cooperation |
| SIT | Special Investigation Team |
| SHO | Station House Officer |
| SDM | Sub Divisional Magistrate |
| SMPS | Switched-Mode Power Supply |
| SONAR | Sound Navigation and Ranging |
| SENSEX | Stock Exchange Sensitive Index |
| SIP | Systematic Investment Plan |
| SKU | Stock Keeping Unit |
| SLA | Service Level Agreement |
| STD | Sexually Transmitted Diseases |
| STD | Subscriber Trunk Dialing |
| SWAT | Special Weapons and Tactics |
| SOS | Save Our Souls |
| SAP | systems, applications, and products |
| SMH | Shaking My Head |
| SP | Samajwadi Party |
| SEO | Search Engine Optimization |
| SIM | Subscriber Identity Module |
| SMS | Short Message Service |
| SQL | Structured Query Language |
| SGPT | Serum Glutamic Pyruvic Transaminase |
| SSD | Solid-State Drive |
| SOP | Standard Operating Procedure |
| SATA | Serial AT Attachment |
| SAS | Statistical Analysis System |
| SGOT | Serum Glutonic Oxaloacetic Transaminase |
| SSL | Secure Sockets Layer |
| SNH | Sarcasm Noted Here |
| SFLR | Sorry, for late Reply |
| SCNR | Sorry, could not Resist |
| SRY | Sorry |
| SAT | Scholastic Assessment Test |
| SPSS | Statistical Packages for the Social Sciences |
| SSC FCI | Staff Selection Commission Food Corporation of India |
| SSC JE | Staff Selection Commission Junior Engineer |
| SSC GD | Staff Selection Commission General Duty |
| SSC MTS | Staff Selection Commission Multitasking Staff |
| SSC CHSL | Staff Selection Commission Combined Higher Secondary Level |
| SSC CGL | Staff Selection Commission Combined Graduate Level |
| SSC CPO | Staff Selection Commission Central Police Organization |
| SBI Clerk | State Bank of India Clerk |
| SBI PO | State Bank of India Probationary Officer |
| SBI SO | State Bank of India Specialist Officer |
| SOB | Shortness Of Breath |
| SAKT Time Zone | Sakhalin Time (Standard Time) |
| SAMT Time Zone | Samara Time (Standard Time) |
| SAST Time Zone | South Africa Standard Time (Standard Time) |
| SBT Time Zone | Solomon Islands Time (Standard Time) |
| SCT Time Zone | Seychelles Time (Standard Time) |
| SRET Time Zone | Srednekolymsk Time (Standard Time) |
| SST Time Zone | Samoa Standard Time (Standard Time) |
| SYOT Time Zone | Syowa Time (Standard Time) |
